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. 2011 Jul;2(3):201–225. doi: 10.1177/1947603510392914

Figure 3.

Figure 3.

Direct rAAV-mediated gene transfer to rabbit meniscus explants in vitro using an rAAV-lacZ (left panel) or rAAV-hFGF-2 vector (right panel) (50 mL each vector). Persistent transgene expression after 10 days in vitro in meniscal explants following immunohistochemical detection of lacZ (A), while no signal is present in the control (B). Direct transduction of a rabbit meniscal explant with rAAV-hFGF-2 results in an increased cell density (D) compared with the control (C), indicative of the mitogenic effect of FGF-2 on meniscal fibrochondrocytes. (C, D) hematoxylin and eosin/fast green. All magnifications, 20x.