Table 3.
Average number of pvmsp-7 gene synonymous substitutions per synonymous site (d S ) and non-synonymous substitutions per non-synonymous site (d N )
| n | Gene | 5′-end | Central | 3′-end | Full-length gene | ||||
|---|---|---|---|---|---|---|---|---|---|
| Worldwide isolates | dS(SE) | dN(SE) | dS(SE) | dN(SE) | dS(SE) | dN(SE) | dS(SE) | dN(SE) | |
| 35 | msp-7E | 0.0488 (0.0118)• | 0.0082 (0.0032) | 0.0717 (0.0163) | 0.1573 (0.0134)• | 0.0665 (0.0130)• | 0.0171 (0.0045) | 0.0626 (0.0078) | 0.0551 (0.0055) |
| 41 | msp-7F | 0.0000 (0.0000) | 0.0000 (0.0000) | 0.0000 (0.0000) | 0.0013 (0.0012) | 0.0000 (0.0000) | 0.0018 (0.0018) | 0.0000 (0.0000) | 0.0011 (0.0007)^ |
| 36 | msp-7L | 0.0006 (0.0005) | 0.0000 (0.0000) | 0.0000 (0.0000) | 0.0012 (0.0008) | 0.0013 (0.0012) | 0.0008 (0.0008) | 0.0006 (0.0005) | 0.0007 (0.0004) |
| Colombian isolates | |||||||||
| 31 | msp-7E | 0.0473 (0.0115)• | 0.0079 (0.0032) | 0.0706 (0.0168) | 0.1549 (0.0135)• | 0.0633 (0.0124)• | 0.0161 (0.0042) | 0.0606 (0.0077) | 0.0539 (0.0056) |
| 36 | msp-7F | 0.0000 (0.0000) | 0.0000 (0.0000) | 0.0000 (0.0000) | 0.0012 (0.0011) | 0.0000 (0.0000) | 0.0017 (0.0016) | 0.0000 (0.0000) | 0.0010 (0.0007)^ |
| 31 | msp-7L | 0.0000 (0.0000) | 0.0000 (0.0000) | 0.0000 (0.0000) | 0.0012 (0.0009) | 0.0010 (0.0010) | 0.0009 (0.0008) | 0.0004 (0.0004) | 0.0007 (0.0004) |
SE: standard error. 5′-end (pvmsp-7E: nucleotide 1–390, pvmsp-7F: nucleotide 1–432, pvmsp-7L: nucleotide 1–381), central (pvmsp-7E: nucleotide 391–747, pvmsp-7F: nucleotide 433–1,053, pvmsp-7L: nucleotide 382–816) and 3′-end (pvmsp-7E: nucleotide 748–1,158, pvmsp-7F: nucleotide 1,054–1,449, pvmsp-7L: nucleotide 817–1,275). Numbering based on Additional files 4, 9 and 10. ^: p = 0.06, •: p <0.001.