Table 2.
Gene expression alterations of stem cell-related genes in mesenchymal stem cells and diffuse-type gastric cancer
| Gene symbol | Gene name | P value | Ratio of diffuse-type GC to MSCs | Probe set ID |
| NANOG | Nanog homeobox | 0.0037 | 14.9 | 220184_at |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0022 | 35.4 | 1566191_at |
| TNFRSF8 | Tumor necrosis factor receptor superfamily, member 8 | 0.0126 | 1.98 | 206729_at |
| CD9 | CD9 molecule | 0.0012 | 3.44 | 201005_at |
| ICAM3 | Intercellular adhesion molecule-3 | 0.0143 | 2.69 | 204949_at |
| CD200 | CD200 molecule | 0.0013 | 4.79 | 209583_s_at |
| 0.0002 | 4.35 | 209582_s_at | ||
| THY1 | Thy-1 cell surface antigen | 0.0081 | 0.61 | 208850_s_at |
| 0.0301 | 0.79 | 208851_s_at | ||
| 0.0024 | 0.67 | 213869_x_at |
Genes related to stem cells in the literature are shown with their gene expression alterations in MSCs and diffuse-type GC. NANOG and SUZ12, which have been found by gene expression analysis to be involved in MSC invasion was up-regulated in diffuse-type GC compared to MSCs. RGS: Regulator of G-protein signaling; MSCs: Mesenchymal stem cells; GC: Gastric cancer.