Table 3.
Gene expression alterations of epithelial-mesenchymal transition-related genes in mesenchymal stem cells and diffuse-type gastric cancer
| Gene symbol | Gene name | P value | Ratio of diffuse-type GC to MSCs | Probe set ID |
| TWIST1 | Twist family bHLH transcription factor 1 | 0.0004 | 0.2 | 213943_at |
| PRRX1 | Paired related homeobox 1 | 1.00E-05 | 0.3 | 226695_at |
| ZEB2 | Zinc finger E-box binding homeobox 2 | 0.027 | 2.1 | 203603_s_at |
| 0.03 | 1.7 | 228333_at | ||
| 6.00E-05 | 3.9 | 235593_at | ||
| TJP1 | Tight junction protein 1 | 0.184 | 1.2 | 202011_at |
| 0.795 | 1 | 214168_s_at | ||
| CTNNB1 | Catenin (cadherin-associated protein), beta 1, 88 kDa | 0.001 | 9.6 | 223679_at |
| VIM | Vimentin | 0.031 | 4.7 | 1555938_x_at |
| 0.016 | 0.7 | 201426_s_at | ||
| FN1 | Fibronectin 1 | 0.204 | 0.6 | 1558199_at |
| 0.015 | 0.7 | 210495_x_at | ||
| 0.004 | 0.7 | 211719_x_at | ||
| 0.001 | 0.6 | 212464_s_at | ||
| 4.00E-08 | 0.04 | 214701_s_at | ||
| 1.00E-10 | 0.02 | 214702_at | ||
| 0.008 | 0.7 | 216442_x_at | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.187 | 1.2 | 207163_s_at |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 8.00E-09 | 3.1 | 225471_s_at |
| 0.002 | 4.4 | 226156_at | ||
| 0.0006 | 5.6 | 236664_at | ||
| 0.0006 | 7.6 | 1560689_s_at | ||
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0006 | 6.2 | 242876_at |
| 0.008 | 0.6 | 212607_at | ||
| 0.549 | 1.2 | 212609_s_at | ||
| 0.385 | 0.8 | 219393_s_at | ||
| 0.772 | 1.1 | 222880_at | ||
| 0.0003 | 0.5 | 242879_x_at | ||
| SFN | Stratifin | 0.003 | 66 | 33322_i_at |
| 0.008 | 111 | 33323_r_at | ||
| EPCAM | Epithelial cell adhesion molecule | 0.0009 | 725 | 201839_s_at |
| F11R | F11 receptor | 0.0004 | 35 | 221664_s_at |
| 0.002 | 21 | 222354_at | ||
| 0.0009 | 201 | 223000_s_at | ||
| 0.012 | 25 | 224097_s_at | ||
| GJB2 | Gap junction protein, beta 2, 26 kDa | 0.023 | 69 | 223278_at |
| LEF1 | Lymphoid enhancer-binding factor 1 | 0.002 | 26 | 221558_s_at |
| JUN | Jun proto-oncogene | 0.042 | 4.8 | 201464_x_at |
| 0.022 | 5.1 | 201466_s_at | ||
| 0.079 | 3.8 | 201465_s_at | ||
| 0.019 | 4.1 | 213281_at | ||
| TGFB1 | Transforming growth factor, beta 1 | 0.002 | 2 | 203085_s_at |
| TGFB2 | Transforming growth factor, beta 2 | 0.07 | 0.4 | 209909_s_at |
| 0.055 | 0.6 | 220407_s_at | ||
| 0.588 | 0.8 | 228121_at | ||
| TGFB3 | Transforming growth factor, beta 3 | 0.015 | 6.8 | 209747_at |
| SP1 | Sp1 transcription factor | 0.0002 | 3.4 | 224754_at |
| 2.00E-05 | 2.7 | 224760_at | ||
| HMGA2 | High mobility group AT-hook 2 | 0.003 | 0.3 | 208025_s_at |
| ITGA5 | Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.007 | 0.5 | 201389_at |
| OCLN | Occludin | 0.0008 | 8 | 231022_at |
| 0.012 | 9.4 | 235937_at | ||
| 0.027 | 11 | 209925_at | ||
| 0.0045 | 11 | 227492_at | ||
| CXADR | Coxsackie virus and adenovirus receptor | 0.013 | 265 | 203917_at |
| 0.014 | 297 | 226374_at | ||
| 0.021 | 75 | 239155_at | ||
| KRT8 | Keratin 8 | 0.012 | 128 | 209008_x_at |
RGS: Regulator of G-protein signaling; MSCs: Mesenchymal stem cells; GC: Gastric cancer.