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Patchy Mel1b receptor distribution in the OPL resembles the distribution of cone terminals. Mel1b receptor labeling in retinal flatmounts confirms the localization of Mel1b to discrete patches of processes (arrows) in the OPL, reminiscent of cone terminal distribution. The patches of Mel1b receptor labeling tend to form annuli surrounding a center region devoid of Mel1b labeling (*). Confocal image stack comprised of 18 optical slices of ≈400 nm each. Scale bar = 10 μm.
