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. Author manuscript; available in PMC: 2015 Jan 21.
Published in final edited form as: Nanoscale. 2014 May 7;6(9):4765–4773. doi: 10.1039/c3nr06400j

Fig. 4.

Fig. 4

Representative fluorescence microscopy images (scale bar 100 μm) and quantitative fluorescence intensity data of interaction of rhodamine-labeled (red) VBP-decorated constructs to glass coverslip-adsorbed FVIII-free VWF in the presence or absence of ristocetin (Risto) treatment with additional presence or absence of glycocalicin (Glyco) pre-incubation. The constructs were found to substantially bind to VWF even when Glyco pre-incubation (VWF A1 blocking) was used, and this binding was significantly reduced (p < 0.001) only when the VBP-decorated constructs were exposed to BSA or undecorated constructs were exposed to the VWF surface. The constructs showed only slightly lower binding to VWF without Risto treatment.