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. 2014 Dec 23;7:102. doi: 10.1186/s13039-014-0102-7

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© Trofimova et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Hypothetical scheme of PO41 repeat transcripts structure in different nuclear compartments. PO41 repeat transcripts are shown in red, elongating form of RNA polymerase II – in green, nucleoplasm and chromatin – in blue. Major foci of PO41 repeat transcripts associated with RNA polymerase II presumably represent nascent RNA (a) while dispersed PO41 repeat transcripts localized in euchromatin or interchromatin space presumably represent released RNA (b). In interphase nucleus, PO41 RNA is single-stranded with short double-stranded regions due to appearance of inverted repeats (b).