Skip to main content
. 2014 Dec 24;17(2):358–361. doi: 10.1021/ol5034805

Table 2. Phosphine Ligand Screen.

graphic file with name ol-2014-034805_0006.jpg

entrya ligand % yield (2a + 2b)b 2a:2bb
1 PPh3 93% 6:94
2 tetrahydrothiophene 54% 6:94
3 triethyl phosphite 73% 6:94
4 MePhos 20% 15:85
5 DavePhos 13% 46:56
6 TrixiePhos 92% 10:90
7 Cy3P 98% 6:94
8 (i-Pr)3P 97% 4:96
a

See Table 1 for reaction conditions. Reactions assembled in a nitrogen-containing glovebox.

b

Yield and product ratio obtained via GC; see Supporting Information for details.