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. 2014 Dec 16;89(1):468–479. doi: 10.1128/JVI.02077-14

TABLE 3.

Quantification of cellular inflammation in histological specimens

Score Description
Severitya
    0 No inflammatory infiltrates
    1 Inflammatory cells present without discrete foci
    2 Larger foci of 10 to 100 inflammatory cells
    3 Larger foci of >100 inflammatory cells
Extent
    1 Mild (<25% of section involved)
    2 Moderate (∼25–75% of section involved)
    3 Severe (>75% of section involved)
a

A score from 0 to 3 was given for the size/intensity of cellular infiltrates. The score was then multiplied by a number reflecting the extent of involvement in the specimen to reach a single final severity score, resulting in a total score that could range from 0 to 9.