FIG 5.

Differentiated AP-7 neurons also restrict multiplication of LACV. cAP-7 (dashed lines) or dAP-7 (solid lines) neurons were infected with the original strain of LACV (MOI, 5). Viral titers in supernatant fluids collected at the indicated times after infection were measured by plaque formation on BHK cells and are expressed as the mean log₁₀ PFU/ml ± standard deviation of triplicate samples from a representative of two experiments. Significant differences between cAP-7 and dAP-7 at each time point were determined by two-way ANOVA with Bonferroni's posttest. ***, P < 0.001.