FIG 6.

ORF119L overexpression results in cardiac defects in zebrafish. (A to D) Paraffin section and H&E staining in control (A and C) and ORF119L-overexpressing (B and D) embryos at 3 dpf. The arrowheads indicate the ventricular wall. (E to H) TEM assay detecting the ultracellular structure of ventricle muscle in control (E and G) and ORF119L-overexpressing embryos (F and H) at 3 dpf. Images in panels C, D, G, and H showed higher magnifications of the boxed areas in panels A, B, E, and F, respectively. PC, pericardial cavity; v, ventricle; a, atrium; S*, sarcomeric structure. Bars = 500 μm (A and B), 100 μm (C and D), 2 μm (E and F), and 500 nm (G and H).