TABLE 3.
Multivariate analysis of HIV-1 monocyte apoptosisa
| Apoptosis type | Statistic | Coefficient | Estimate | SE | 95% CI | t value | P value |
|---|---|---|---|---|---|---|---|
| Constitutive | Intercept | 6.445281 | 2.2119471 | 1.8695 to 11.0210 | 2.914 | 7.82E−03 | |
| IFI27 | 0.003723 | 0.0008659 | 0.001932 to 0.005514 | 4.299 | 2.67E−04 | ||
| IFITM2 | −1.24797 | 0.6839378 | −2.6628 to 0.16686 | −1.825 | 0.081066 | ||
| Rb1 | 0.393577 | 0.3363558 | −0.3022 to 1.0894 | 1.17 | 2.54E−01 | ||
| Bcl2 | 1.811856 | 0.4172257 | 0.9488 to 2.6750 | 4.343 | 2.40E−04 | ||
| Multiple R2 | 0.6578 | ||||||
| Adjusted R2 | 0.5983 | ||||||
| F statistic | 11.05 on 4 and 23 DF | ||||||
| P value | 3.77E-05 | ||||||
| Induced | Intercept | −98.354 | 21.986 | −143.9495 to −52.7577 | −4.473 | 1.90E−04 | |
| Log viral load | 19.890 | 3.532 | 12.5647 to 27.2153 | 5.631 | 1.16E−05 | ||
| IFITM2 | −5.899 | 4.277 | −14.7694 to 2.9718 | −1.379 | 0.18173 | ||
| Rb1 | 15.037 | 5.332 | 3.978022 to 26.0957065 | 2.820 | 0.00997 | ||
| Bax | −16.529 | 8.200 | −33.534222 to 0.4762045 | −2.016 | 0.0562 | ||
| Multiple R2 | 0.6612 | ||||||
| Adjusted R2 | 0.5996 | ||||||
| F statistic | 10.73 on 4 and 22 DF | ||||||
| P value | 5.59E-05 |
a
SE, standard error; CI, confidence interval; DF, degrees of freedom.