FIG 4.
Lung viral load in BALB/c mice. (A and B) BALB/c mice were inoculated with 106 (A) or 105 (B) PFU of the indicated viruses, and left lungs were harvested on day 1, 2, or 4, postinfection. Viral titers were determined by immunodetection plaque assay. The dotted lines represent the limit of detection. Groups significantly different compared to A2-line19F are indicated by cross bars. Data are combined from three independent experiments, each with 4 or 5 mice per group. (A) *, P < 0.05; **, P < 0.001, by one-way ANOVA with Tukey multiple-comparison test; (B) *, P < 0.01; **, P < 0.001, by one-way ANOVA with Tukey multiple-comparison test.