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. 2014 Oct 27;112(12):1914–1922. doi: 10.1017/S0007114514002578

Table 3.

Mean values of post- v. pre-diet changes in both ratios of total cholesterol (TC):HDL-cholesterol (HDL-C) and LDL-cholesterol (LDL-C):HDL-C v. doses of ruminant-18 : 1 trans-fatty acids in the diet for the twenty-three experimental groups of subjects

Study identification Experimental group* Total R-18 : 1t (% EI) Total R-18 : 1t (g/d) TC:HDL-C change LDL-C:HDL-C change
Wood( 29 ) (1993) Butter 2·00 5·84 0·01 0·02
Almendingen( 31 ) (1995) Butter 0·50 1·33 0·16 0·35
Aro( 30 ) (1997) Run-in 0·80 2·29 0·14 0·04
Run-in 0·80 2·29 0·37 0·27
Tholstrup( 24 ) (1998) Danish milk 0·12 0·44 0·10 0·09
Milk fat 1·66 6·18 0·26 0·18
Lichtenstein( 20 ) (2003) Butter 1·00 3·1 0·57 0·43
Butter 1·00 2·35 0·28 0·36
Biong( 26 ) (2004) Cheese 0·68 1·53 0·10 0·11
Desroches( 28 ) (2005) Control 0·25 0·83 − 0·41 − 0·19
CLA 1·69 5·52 − 0·02 0·08
Tholstrup( 10 ) (2006) Control 0·32 1·17 0·27 0·29
Vaccenic acid 2·14 7·54 0·24 0·19
Tricon( 27 ) (2006) Control 0·27 0·78 − 0·03 − 0·03
CLA 2·10 6·34 0·18 0·09
Chardigny( 3 ) (2008) R-TFA 4·19 10·03 0·07 0·03
R-TFA 4·19 8·82 0·10 0·07
Motard-Bélanger( 4 ) (2008) Moderate 1·45 5·4 0·23 0·47
High 3·50 13·21 0·57 0·79
Malpuech-Brugère( 25 ) (2010) L0 0·61 1·42 0·05 0·05
L4 0·87 1·98 − 0·12 0·00
L9 2·42 5·38 0·02 0·11
Lacroix( 11 ) (2012) R-TFA 1·40 3·54 0·31 0·30

% EI, percentage of energy intake; CLA, conjugated linoleic acid; R-TFA, ruminant trans-fatty acid; L0, experimental dairy fat containing 2·9 g R-TFA for 100 g fatty acids; L4, experimental dairy fat containing 4·1 g R-TFA for 100 g fatty acids; L9, experimental dairy fat containing 12·2 g R-TFA for 100 g fatty acids.

*

Experimental group, as named in the original articles.