Figure 1. Impact of persistent or resolved renal laboratory abnormalities on development of new renal disease diagnoses.
The Flow chart depicts the outcome in developing new renal diagnosis based on renal laboratory screening tests that persist or resolve. There were 1874 children in the study cohort with no renal laboratory abnormalities nor renal diagnosis at study entry. During follow-up, 428 (23%) developed new renal laboratory abnormalities while 1446 (77%) did not. Of those cases with new renal laboratory abnormalities, 229 (54%) had persistence of abnormal laboratory renal studies with 35 (15.3%) developing a new renal diagnosis. In contrast, 199 (46%) had resolution of their abnormal renal studies with only 5 (2.5%) developing a new renal diagnosis. In the 1446 (77%) cases that never developed new renal laboratory abnormalities, there were 39 (2.7%) who developed renal diagnosis.