Table 5.

The association between personal characteristics and HIV disease markers and time to abnormal renal lab (RLE) resolution for three separate analyses, considering time-varying HIV disease markers and HIV disease markers at the first RLE^†.

Analysis set	Parameter	Unadjusted Results		Adjusted Results
		Hazard Ratio (95% CI)	P-value	Hazard Ratio (95% CI)	P-Value
Analysis 1:, time varying CD4, RNA	Race, Black	0.82 (0.6,1.1)	0.15	0.80 (0.6,1.1)	0.15
	CDC Stage C	0.73 (0.5,1.0)	0.08	0.72 (0.5,1.1)	0.09
	CD4 pct < 25 (time-varying)	0.71 (0.5,1.0)	0.03 *	0.75 (0.6,1.0)	0.06
Analysis 2: CD4, RNA @ RLE	Race, Black	0.82 (0.6,1.1)	0.15	0.78 (0.6,1.1)	0.13
	CDC Stage C	0.73 (0.5,1.0)	0.08	0.71 (0.5,1.0)	0.08
	HIV RNA copies > 100,000 at RLE	0.30 (0.1,0.7)	0.004 *	0.31 (0.1,0.7)	0.01 *
Analysis 3: CD4 @ RLE	CD4 pct < 25 at RLE	0.63 (0.5,0.8)	0.002 *	0.63 (0.5,0.8)	0.002 *

Note: These results only show core variable models. Core models were built with p < 0.20 to include and p < 0.15 to retain.

^*p < 0.05

^†These analyses were carried out on the primary derived dataset, formed using medication exposure observations as the framework, adding in CD4 and RNA viral load values.