Table I.
Tumor characteristics.
| Group | n | TV, mm3 | TIR, % | HK, U/gprot | AOD |
|---|---|---|---|---|---|
| 3-BrPA high-dose | 11 | 699.9±86 | 45.1a | 19.62±5.57 | 0.10±0.017 |
| 3-BrPA medium-dose | 12 | 762.5±79 | 40.2a | 46.26±8.68 | 0.07±0.009 |
| 3-BrPA low-dose | 12 | 835.1±98 | 34.5a | 67.38±13.55 | 0.05±0.009 |
| 5-FU | 11 | 671.9±52 | 47.3a | 103.73±8.50 | 0.16±0.057 |
| NS | 12 | 1293.8±93 | - | 115.81±8.45 | 0.04±0.008 |
Values are expressed as the mean ± standard deviation.
a
P<0.05 vs. the NS group.
TV, tumor volume; TIR, tumor inhibition rate; HK, hexokinase; AOD, average optical density; 3-BrPA, 3-bromopyruvate; 5-FU, 5-fluorouracil; NS, normal saline.