Table I.
Capecitabine maintenance | HRT maintenance | ||||
---|---|---|---|---|---|
|
|
||||
Characteristics | n | % | n | % | P-value |
Menopause status | 0.406 | ||||
Pre | 12 | 30.8 | 9 | 22.5 | |
Post | 27 | 69.2 | 31 | 77.5 | |
ECOG PS | 0.372 | ||||
0 | 23 | 59.0 | 30 | 75.0 | |
1 | 14 | 35.9 | 9 | 22.5 | |
2 | 2 | 5.1 | 1 | 2.5 | |
HR status | 0.082 | ||||
Positive | 28 | 71.8 | 35 | 87.5 | |
Negetive | 11 | 28.2 | 5 | 12.5 | |
Lymph nodes, na | 0.516 | ||||
0–3 | 28 | 71.8 | 26 | 65.0 | |
≥4 | 11 | 28.2 | 14 | 35.0 | |
Her-2 status | 0.876 | ||||
Positiveb | 6 | 15.4 | 5 | 12.5 | |
Negativec | 32 | 82.1 | 34 | 85.0 | |
Unknown | 1 | 2,4 | 1 | 2.5 | |
Metastatic site | |||||
Liver | 14 | 35.9 | 12 | 30.0 | 0.577 |
Lung | 23 | 59.0 | 18 | 45.0 | 0.214 |
Bone | 20 | 51.3 | 21 | 52.5 | 0.914 |
Brain | 3 | 7.7 | 4 | 10 | 1.000 |
Soft tissue | 22 | 56.4 | 30 | 75.0 | 0.082 |
Visceral metastasis | 0.210 | ||||
Yes | 32 | 82.1 | 28 | 70.0 | |
No | 7 | 17.9 | 12 | 30.0 | |
Metastatic sites, n | 0.943 | ||||
1 | 7 | 17.9 | 8 | 20.0 | |
2 | 18 | 46.2 | 17 | 42.5 | |
≥3 | 14 | 35.9 | 15 | 37.5 | |
Disease-free interval, years | 0.539 | ||||
<2 | 13 | 33.3 | 16 | 40.0 | |
≥2 | 26 | 66.7 | 24 | 60.0 | |
Prior adjuvant chemotherapy | 0.523 | ||||
Taxane | 20 | 51.3 | 20 | 50.0 | |
Anthracycline | 35 | 89.7 | 27 | 67.5 | |
Prior adjuvant endocrine therapy | 25 | 64.1 | 27 | 67.5 | 0.764 |
Prior palliative endocrine therapy | 17 | 43.5 | 13 | 32.5 | 0.310 |
Lymph nodes, n indicates the number of metastatic lymph nodes;
HR-positive status indicates estrogen and/or progesterone receptor-positive;
HR-negative status indicates estrogen and progesterone receptor-negative.
HRT, hormone replacement therapy; ECOG PS, Eastern Cooperative Oncology Group Performance Status; HR, hormone receptor; Her-2, human epidermal growth factor receptor-2.