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Effect of Shikonin on the expression of FAK, Tyr-397 phospho-FAK, Src and Tyr-416 phospho-Src protein in SKOV-3 cells. Western blot analysis demonstrated inhibition of FAK and Src protein expression levels following treatment with dimethyl sulfoxide (control) or 0, 4, 8 or 16 μM shikonin. FAK, focal adhesion kinase; Src, proto-oncogene tyrosine protein kinase Src.
