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Immunohistochemical analysis revealing new vascular endothelial cells (magnification, ×400). Cluster of differentiation 31-stained endothelial cells and endothelial cell clusters were brown and clearly separated from adjacent microvessels, tumor cells or connective tissue elements. A) NS group, B) Endostar group, C) cisplatin group, D) Endostar + cisplatin group and E) Endostar first group. Red arrows indicate the formation of new blood vessels.
