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. 2014 Nov 24;9(2):721–726. doi: 10.3892/ol.2014.2733

Table II.

Clinical characteristics of patients with HCC metastasis to the orbit published since 2009.

Study Author, year Gender/Age, years Side Cerebrum invasion Other metastasis Clinical presentation Risk factor for metastasis
Quick et al, 2009 M/52.0 R No No Proptosis and diplopia No
Kolarevic et al, 2011 M/70.0 R No Spleen, maxillary, retroperitoneal lymph node Bleeding difficult to control after dental surgery No
Mustapha et al, 2011 M/25.0 R No No Progressive pain, swelling and blurred vision for 1 month NR
Guerriero et al, 2011 M/45.0 L Yes Lung Proptosis for 1 month HCC liver transplant 5 years previously
Piccirillo et al, 2013 NA L No Lung NR HCC liver transplant 3 years previously
Eldesouky et al, 2013 M/62.0 L No No Painful proptosis for 8 weeks HCC for 1.5 years
M/70.0 L No No Painful proptosis for 6 weeks HCV for 10 years
M/55.0 R No No Proptosis for 4 weeks HCC for 1 year
M/65.0 L No No Painful proptosis for 2 weeks HCV for 12 years
M/47.0 L No No Painful proptosis for 6 weeks HCV for 15 years
M/62.0 R Yes No Eyelid ptosis for 8 weeks HCC for 14 months
Present study M/43.5 L Yes No Mild headache and mild protopsis for 4 weeks HCC for 5 months

M, male; R, right; L, left; HCC, hepatocellular carcinoma; HCV, hepatitis C virus infection; NR, not reported.