Table 1.

Flowchart data collection

	Baseline	1-year FU	2-year FU
Informed consent	X
Clinical data	X	X	X
Cognitive assessment	X	X	X
Scales and questionnaires	X	X	X
Blood (serum and plasma)	X		X
DNA	X		X
MRI	X		X
CSF (optional)	X

DNA: Deoxyribonucleic Acid, MRI: Magnet Resonance Imaging, CSF: Cerebrospinal fluid.