Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The stacking effect. (A) The correct multiple alignment of seven sequences. (B) The multiple alignment of the same seven sequences, with the stacking effect. When only gap-open and gap-continue penalties are used, the stacked alignment (B) incurs one gap-open penalty less than the correct alignment (A), and therefore is optimal. When gap-end penalties are used, the correct alignment (A) is optimal because it incurs two gap-end penalties less than the stacked alignment (B).
