Table 3.
Changes in Performance of LAGAN and MLAGAN on the CFTRDataset When Translated Anchoring Is Enabled
| Alignment | Aligner | 100% | 90%+ | 70%+ | Time diff. |
| Human/chicken | LAGAN | −2% | −3% | −3% | +25% |
| MLAGAN | 0% | 0% | 0% | — | |
| Human/fugu | LAGAN | +6% | +8% | +8% | +93% |
| MLAGAN | +4% | +3% | +1% | — | |
| Human/zebrafish | LAGAN | +7% | +6% | +4% | +29% |
| MLAGAN | 0% | 0% | 0% | — | |
| Total for all 11 | LAGAN | +1% | 0% | +1% | +60% |
| alignments | MLAGAN | 0% | +1% | 0% | +66% |
We report the differences in the percentage of exons correctly aligned with translated anchoring vs. with the default options where translated anchoring is disabled. No changes were observed in the alignments between mammalian sequences.