Figure 3.
Orolingual motor measures as a function of age and drug dose. (A) Number of licks per session was increased by GBR-12909, but only in the young rats (xp<0.05). Unlike GBR-12909, amphetamine increased number of licks per session in both groups (*p<0.001). Post hoc analysis revealed that this effect was significant only at 1 mg/kg (pp<0.05). (B) Peak tongue force was greater in the old group (#p<0.05), and was not affected by GBR-12909. Amphetamine decreased peak force, but only in the older rats (xp<0.01). (C) Licking speed was slower in the older group (#p<0.001). This measure was increased by amphetamine (*p<0.05). Post hoc analysis revealed that this effect was significant only at 1 mg/kg (pp<0.05). Explanation of symbols: *main effect for drug; #main effect for age; xdrug-by-age interaction; psignificant post-hoc comparison.
