Table 2.

Base-case cost estimates ($, year 2013 values) and utilities

Parameter	Median	Range	Description and reference
Costs
Cost of capecitabine per 500 mg	6.6	Fixed	Local charge
Cost of S-1 per 20 mg	9.6	7.9 - 10.1	Local charge
Cost of oxaliplatin per 50 mg	88.9	77.3 - 464.5	Local charge
Cost of follow-up per unit	56.5	42.3 - 70.6	Calculation
Cost of tests per 6-weeks of adjuvant with S-1	197.8	15.9 - 317.5	[31]
Cost of salvage chemotherapy per 3-week cycle	2334.6	1429.3 - 3323.2	Calculation
Cost of palliative end-of-life care	1460.3	1055.3 - 2085.7	Calculation
Cost of supportive care per cycle	115.2	31.7 - 317.5	Calculation
Cost of ADR per 6-week period of adjuvant with S-1	42.3	7.9 - 79.4	[31]
Cost of ADR per 3-week cycle of adjuvant with XELOX strategy	68.9	15.9 - 158.7	[31]
Cost of hospitalization per 3-week cycle of adjuvant with XELOX strategy	373	238.1 - 793.7	[31]
Utilities
Utility of disease-free survival	0.88	0.8 - 0.97	Measured
Utility of recurrent disease	0.42	0.28 - 0.63	Measured

Key: “&” Values were measured by time trade-off (TTO).