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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Cancer Res. 2014 Nov 11;75(1):51–61. doi: 10.1158/0008-5472.CAN-14-0820

Figure 3.

Figure 3

Phenotypic analysis of APC activation markers in DLN on day 6. A) Representative analysis of mice vaccinated with GVAX alone (A) and GVAX+GLA (B). EverGreen+ CD11c+ cells (blue) show increased expression of activation markers CD86 and CD40 in mice vaccinated with both GVAX and GVAX+GLA compared to EverGreen-CD11c+ cells (red) and EverGreen-CD11c- cells (orange) in both groups. A population of EverGreen-CD11c+ cells also exhibit upregulated activation markers but not to the extent seen for EverGreen+CD11c+ cells. The expression level of MHC-II in EverGreen+CD11c+ cells (blue) in both groups was comparable to EverGreen- CD11c+ cells (red). The expression levels of these markers were not significantly different between the two vaccinated groups.