Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Nov 24;15(1):1016. doi: 10.1186/1471-2164-15-1016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Tokunaga et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Characteristics of ENU mutagenesis in haploid ESCs. (A) Mutation types detected by whole-exome analysis. Actual numbers of mutations are shown in parentheses through Figure 3A–C. (B) Frequencies of nucleotide changes. The 2,240 point mutations are classified as transitions or transversions. Fewer than 2.5% of the 2,296 single-nucleotide substitutions could not be classified by our WES analytical pipeline for unknown reasons. We excluded these data from the analysis in Figure 3B. (C) Effects of mutations on genes predicted by SnpEff software (see also Additional file 6: Table S12). If more than one effect was annotated on a single mutation, effects with higher impact prediction were adopted.