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. 2014 Dec 15;14:958. doi: 10.1186/1471-2407-14-958

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© Doberstein et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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L1CAM mRNA expression correlates negatively to AR expression in the Hamburg cohort. (A) Scatter plot of L1CAM mRNA expression to AR mRNA expression. Values are given in (RNA Seq V2 RSEM) in log2. n = 219, r = -0.294, P < 0.0001. Kaplan Meier analysis of disease free survival (B) (AR pos, L1CAM neg vs. AR neg L1CAM pos: P = 0.005) and overall survival (C) (AR pos, L1CAM neg vs. AR neg L1CAM pos: P < 0.001) of cases that express different combination of L1CAM and AR. L1CAM^low/AR^high (blue line), L1CAM^low/AR^low (green line), L1CAM^high/AR^high (red line), L1CAM^high/AR ^low (violet line).