Table 1.
Clinical and histopathological characteristics of the Hamburg and the Innsbruck cohorts of breast cancer patients
| Hamburg n = | Innsbruck n = | |
|---|---|---|
| Total number of cases | 219 | 60 |
| Patient data available | 198 | 53 |
| Date of surgery: | 1990 - 2003 | 2001 - 2010 |
| Age: | ||
| Mean (year) | 56.8 | 58.7 |
| Median (year) | 56.6 | 58.5 |
| Range | 29.3 - 93.5 | 33 - 84 |
| Stage (pT) | ||
| 1 | 51 | 3 |
| 2 | 122 | 27 |
| 3 | 10 | 28 |
| 4 | 10 | 0 |
| Unknown | 5 | 2 |
| Nodal status | ||
| Negative | 137 | 33 |
| Positive | 60 | 25 |
| Unknown | 1 | 2 |
| Grading | ||
| G1 | 20 | 1 |
| G2 | 81 | 42 |
| G3 | 92 | 15 |
| Unknown | 5 | 0 |
| Histological type | ||
| Ductal | 141 | 60 |
| Lobular | 31 | 0 |
| Others | 22 | 0 |
| Unknown | 4 | 0 |
| Estrogen receptor (ER) status1 | ||
| Positive | 149 | 0 |
| Negative | 41 | 60 |
| Unknown | 8 | 0 |
| Progesterone receptor (PR) status1 | ||
| Positive | 125 | 0 |
| Negative | 65 | 60 |
| Unknown | 8 | 0 |
| HER2 (ErbB2) status2 | ||
| Positive | 44 | 0 |
| Negative | 152 | 60 |
| Unknown | 2 | 0 |
| Molecular subtype2 | ||
| Luminal | 121 | 0 |
| HER2-positive | 45 | 0 |
| Triple-negative | 30 | 60 |
| Unknown | 2 | 0 |
| Adjuvant chemotherapy | ||
| Yes | 124 | 56 |
| No | 69 | 2 |
| Unknown | 5 | 2 |
| Follow-up period (months) | ||
| Mean | 120.4 | 67.4 |
| Median | 132.0 | 62.9 |
| Recurrences | 72 | 9 |
| Died of disease | 56 | 8 |
1based on routine immunohistochemical ER/PR staining.
2based on mRNA data using the cut-off values as described [23].