Table 1. Clinicopathologic Characteristics.
| Variables | Triple-Negative Cancer (n = 256) | ER-Positive Cancer (n = 846) | P value |
|---|---|---|---|
| Age (y)a | 51 (20 – 78) | 52 (22 – 84) | .069 |
| Family history of breast cancer | 26 (10.2) | 47 (5.6) | .014 |
| Palpability | < .0001 | ||
| No | 60 (23.4) | 379 (44.8) | |
| Yes | 196 (76.6) | 467 (55.2) | |
| Mammographic breast density | .934b | ||
| Grade 1 | 25 (9.8) | 75 (8.9) | |
| Grade 2 | 56 (21.9) | 185 (21.9) | |
| Grade 3 | 127 (49.6) | 436 (51.5) | |
| Grade 4 | 48 (18.8) | 150 (17.7) | |
| Mammographic visibility | .151 | ||
| No | 19 (7.4) | 83(9.8) | |
| Yes | 237(92.6) | 763(90.2) | |
| Histologic type | |||
| Invasive ductal | 235 (91.8) | 755 (89.2) | .288 |
| Invasive lobular | 0 | 45 (5.3) | < .0001 |
| Mucinous | 0 | 32 (3.8) | < .0001 |
| Metaplastic | 13 (5.1) | 0 | < .0001 |
| Tubular | 0 | 5 (0.6) | .596 |
| Apocrine | 4 (1.6) | 0 | .003 |
| Adenoid cystic | 2 (0.8) | 0 | .054 |
| Invasive papillary | 1 (0.4) | 6 (0.7) | 1.000 |
| Invasive micropapillary | 0 | 2 (0.2) | 1.000 |
| Medullary | 1 (0.4) | 1 (0.1) | .411 |
| Tumor size(cm)a | 2.2 (0.2 – 5.4) | 1.9 (0.2 – 5.9) | < .0001 |
| Histologic grade | < .0001b | ||
| I | 2 (0.8) | 125 (14.8) | |
| II | 35 (13.7) | 478 (56.5) | |
| III | 219 (85.5) | 243 (28.7) | |
| Axillary nodal status | .001 | ||
| Negative | 216 (84.4) | 628 (74.2) | |
| Positive | 40 (15.6) | 218 (25.8) | |
| Surgery | .628 | ||
| Breast-conserving surgery | 212 (82.8) | 712 (84.2) | |
| Mastectomy | 44 (17.2) | 134 (15.8) |
Unless otherwise indicated, data are numbers of patients and numbers in parentheses are percentages.
aData are mean values, with ranges in parentheses.
bChi-square test for trend.