EMAP II AB promotes survival and preserves heart function after chronic myocardial infarction (MI). (A) Kaplan-Meyer survival curve of mice treated with either EMAP II AB or vehicle after 4 week chronic MI. *: p<0.05 compared with vehicle, n=30 for EMAP II AB group, n=28 for vehicle group. (B) EMAP II AB treated mice have preserved left ventricle ejection fraction after both 1 and 4 weeks chronic MI. *:p<0.05 compared with vehicle, n=10 for EMAP II AB group, n=7 for vehicle group. (C) Dynamics of EMAPII expression after chronic MI. EMAP II expression was upregulated one day after MI surgery and continues to be highly expressed at least two weeks after MI as shown with representative western blot (top panel) and quantification (bottom panel). **: p<0.01, *: p<0.05, all compared with Sham.