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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: J Mol Cell Cardiol. 2014 Nov 8;79:104–114. doi: 10.1016/j.yjmcc.2014.10.020

Table 3.

Pressure-Volume Loop analysis of Sham and ACF mice.

Pressure-volume analysis
SHAM ACF
    n= 13 14
    HR [bpm] 564 ± 9 566 ± 6
Systolic Properties
    ESP [mmHg] 95.2 ± 1.2 99.2 ± 2.8
    ESV [mmHg] 20.5 ± 1.2 51.9 ± 2.9***
    SV [μL] 34.4 ± 1.7 61 ± 2.6***
    CO [μl/min] 19379 ± 956 34454 ± 1490***
    EF [%] 63 ± 2 54 ± 2**
    SW [mJoules] 0.45 ± 0.02 0.82 ± 0.03***
    Ea [mmHg/μL] 2.9 ± 0.1 1.7 ± 0.1***
    +dP/dt [mmHg/s] 12122 ± 329 10634 ± 508*
    PVA [mJoules] 0.6 ± 0.03 1.07 ± 0.08***
    ESPVR linear [mmHg/μL] 7.5 ± 0.6 2.9 ± 0.2***
    ESSSR [mmHg/μL] 57.3 ± 3.4 48.4 ± 3.6
Diastolic Properties
    EDP [mmHg] 2.1 ± 0.3 4.5 ± 0.7**
    EDV [μL] 54.8 ± 1.6 112.8 ± 3.6***
    −dP/dt [mmHg/s] −11481 ± 343 −9812 ± 606*
    Tau [ms] 5.0 ± 0.1 5.9 ± 0.2**
    EDPVR linear [mmHg/μL] 0.121 ± 0.008 0.071 ± 0.007***
    EDSSR [mmHg/μL] 2.49 ± 0.23 2.68 ± 0.28

Significant vs. Sham at

*

p<0.05

**

p< 0.01

***

P<0.001

Abbreviations: HR, heart rate: BPM, beats per minute: ESP, end-systolic pressure; ESV, end-systolic volume; SV, stroke volume; CO, cardiac output; EF, ejection fraction percent; SW, stroke work; Ea, arterial afterload; PVA, pressure-volume loop area; ESPVR, end-systolic pressure volume relationship; ESSSR, end-systolic stress-strain relation; EDP, end-diastolic pressure; EDV, end-diastolic volume; EDPVR, end-diastolic pressure volume relationship; EDPVRWV, unitless chamber stiffness; EDSSR, end-diastolic stress-strain relationship.