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Quantification of chemosensitive muscle afferent phenotypes recovered from the ex vivo recording preparations in uninjured (naïve/sham) or combined ischemic (BAO and I/R) mice.
| Response Type | Condition | ASIC3+ | P2X3+ | ASIC3+/P2X3+ |
|---|---|---|---|---|
| High Metabolites | Naïve/Sham | 3/5 | 1/4 | 1/4 |
| Only | Combined Ischemia | 1/4 | 3/3 | 1/3 |
| Low Metabolites | Naïve/Sham | 0/3 | 0/3 | 0/3 |
| Only | Combined Ischemia | nd | nd | nd |
| Low & High | Naïve/Sham | nd | nd | nd |
| Metabolites | Combined Ischemia | 3/6 | 3/6 | 3/6 |
