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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2014 Dec 10;149(1):69–79. doi: 10.1007/s10549-014-3201-6

Fig. 1. P7170 inhibits mTORC1 and mTORC2 kinases in anti-estrogen-sensitive and - resistant ER+ breast cancer cells.

Fig. 1

Lysates from cells treated with 0-400 nM P7170 for 16-24 h were analyzed by immunoblot using the indicated antibodies. Full-length (FL) and cleaved PARP are indicated by arrows. FR cells were treated in the presence of 1 μM fulvestrant. LTED cells were treated in hormone-depleted medium.