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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Exp Cell Res. 2014 Oct 7;331(1):58–72. doi: 10.1016/j.yexcr.2014.09.034

Figure 2. Withaferin A induces apoptosis of ABC-DLBCL cells.

Figure 2

(A) NF-κB activity in the ABC DLBCL cell lines OCI-Ly10 and HBL1, both of which harbor the MYD88 L265P mutation, were treated with WA for 3 hours at the time indicated, as measured by EMSA.

(B) Flow cytometry analysis of WA-induced apoptosis by measuring Annexin V and propidium iodide were 2 days after treatment. The percentage of apoptotic cells is shown.

(C,D) Cell viability of ABC and GCL DLBCL cell lines as measured by trypan blue exclusion assay. Data of time and dose course experiments are shown. Bars represent mean ± SD (N = 3).