Table 1.
Multivariate linear regression analysis for accelerometer-derived sedentary time and cardio-metabolic risk factors
| Model 1 | Model 2 | Model 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Coefficient | 95% CI | P | Coefficient | 95% CI | P | Coefficient | 95% CI | P | |
| Body mass index | 0.119 | (-0.023 to 0.261) | 0.101 | 0.118 | (-0.032 to 0.267) | 0.124 | 0.213 | (0.039 to 0.387) | 0.017 |
| Waist circumference | 0.282 | (-0.132 to 0.696) | 0.181 | 0.262 | (-0.172 to 0.696) | 0.234 | 0.237 | (-0.257 to 0.731) | 0.347 |
| Systolic blood pressure | -0.356 | (-0.944 to 0.231) | 0.234 | -0.188 | (-0.794 to 0.418) | 0.542 | -0.321 | (-1.027 to 0.385) | 0.372 |
| Diastolic blood pressure | -0.206 | (-0.671 to 0.259) | 0.385 | -0.194 | (-0.678 to 0.291) | 0.433 | -0.119 | (-0.684 to 0.446) | 0.679 |
| Triglycerides | 0.048 | (0.027 to 0.068) | <0.001 | 0.055 | (0.033 to 0.076) | <0.001 | 0.046 | (0.021 to 0.071) | <0.001 |
| HDL-Cholesterol | -1.200 | (-1.824 to -0.576) | <0.001 | -1.381 | (-2.045 to -0.717) | <0.001 | -1.312 | (-2.086 to -0.537) | <0.001 |
| Total:HDL ratio | 0.061 | (0.021 to 0.101) | 0.003 | 0.085 | (0.043 to 0.127) | <0.001 | 0.072 | (0.023 to 0.121) | 0.004 |
| LDL-Cholesterol | -0.350 | (-1.602 to 0.902) | 0.583 | 0.595 | (-0.734 to 1.924) | 0.380 | 0.576 | (-0.971 to 2.123) | 0.465 |
| Blood glucose | 0.002 | (-0.003 to 0.008) | 0.421 | 0.005 | (-0.0001 to 0.011) | 0.063 | 0.006 | (-0.001 to 0.012) | 0.088 |
| HbA1c | 0.008 | (0.002 to 0.014) | 0.010 | 0.008 | (0.003 to 0.013) | 0.004 | 0.009 | (0.003 to 0.015) | 0.006 |
Abbreviations: CI confidence interval, HDL-cholesterol high-density lipoprotein cholesterol, LDL-cholesterol low-density lipoprotein cholesterol, HbA1c glycosylated hemoglobin.
Regression coefficients beta corresponding to the mean difference per 60 minutes/day greater sedentary time. Model 1 was adjusted for sex, age, and time accelerometer worn. Model 2 was adjusted for above covariates and educational attainment, marital status, smoking and drinking status, total calorie intake, saturated fat consumption, use of medication, and occupation. Model 3 was adjusted for the same covariates as Model 2 and moderate-to-vigorous physical activity (MVPA). N = 579 for waist circumference, N = 354 for HbA1c, and N = 655–661 for other outcomes due to missing values. Data on triglyceride, blood glucose, and HbA1c were log-transformed.