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. 2014 Dec 12;15(1):405. doi: 10.1186/s12859-014-0405-z

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© Ascensao et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.applies to the data made available in this article, unless otherwise stated.

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A graphical representation of the plus and minus rule. The highlighted nodes represent the ‘successes’ identified by the corresponding rule. a, The plus rule-a pattern whereby if MP₁ and MP₂, then GO₁. b, The minus rule-another pattern whereby if MP₁ and not MP₂, then GO₁.