Table 1.
Patient characteristics
| Characteristic | FD ASAQ | NF ASAQ | P value |
|---|---|---|---|
| N = 26 | N = 28 | ||
| Age | 23.1 (17.9-60.1) | 24.2 (18.1-56.9) | 0.98 |
| Gender (n, M/F) | 12/14 | 13/15 | 0.98 |
| Luo ethnic group [N(%)] | 23 (88.5) | 24 (85.7) | 1.00 |
| Symptoms [N(%)] | |||
| Headache | 23 (88.5) | 26 (92.9) | 0.66 |
| Anorexia | 18 (69.2) | 14 (50.0) | 0.15 |
| Nausea | 16 (61.5) | 17 (60.7) | 0.95 |
| Weakness | 13 (50.0) | 15 (53.6) | 0.79 |
| Vomiting | 12 (46.2) | 16 (57.1) | 0.42 |
| Abdominal pain | 10 (38.5) | 13 (46.4) | 0.55 |
| Diarrhoea | 3 (11.5) | 6 (21.4) | 0.47 |
| Cough | 1 (3.8) | 4 (14.3) | 0.35 |
| Signs (range) | |||
| Weight (kg) | 58.0 (50.0-90.0) | 60.0 (39.0-82.0) | 0.78 |
| Temperature (°C) | 37.2 (36.0-39.0) | 37.2 (35.8-40.0) | 0.42 |
| Pulse rate (beats/min) | 92.5 (62.0-124.0) | 90.5 (57.0-131.0) | 0.90 |
| Systolic blood pressure (mmHg) | 119.5 (90.0-157.0) | 125.5 (85.0-160.0) | 0.48 |
| Diastolic blood pressure (mmHg) | 70.0 (55.0-92.0) | 74.0 (51.0-99.0) | 0.37 |
| Palpable spleen | 0 | 1/27 (3.7) | 1.0 |
| Palpable liver | 0 | 0 | - |
| Laboratory results (range) | |||
| Asexual parasitaemia/µL | 18,479 (8,927-33,915) | 13,742 (5,069-23,948) | 0.56 |
| Gametocyte carriage (n, %) | 1 (3.8) | 0 (0.0) | 0.48 |
| Haemoglobin (g/dL) | 13.3 (10.3-17.6) | 13.2 (9.9-17.7) | 0.53 |
| White blood cells (× 103/µL) | 5.6 (5.2-6.8) | 5.1 (2.3-9.5) | 0.09 |
| Neutrophils (× 103/µL) | 3.5 (1.3-5.6) | 2.6 (0.8-8.1) | 0.02 |
| Lymphocytes (× 103/µL) | 1.3 (0.5-2.5) | 1.3 (0.5-3.3) | 0.22 |
| Monocytes (× 103/µL) | 0.8 (0.6-1.1) | 0.6 (0.4-0.8) | 0.005 |
| Eosinophils (× 103/µL) | 0.07 (0.03-0.58) | 0.08 (0.05-0.19) | 0.60 |
| Platelets (× 103/µL) | 96.0 (44.0-229.0) | 95.5 (18.0-254.0) | 0.86 |
| AST* (IU/L) | 28.0 (13.4-82.9) | 31.2 (15.1-56.1) | 0.99 |
| ALT* (IU/L) | 21.6 (10.5-123.1) | 23.2 (3.8-105.9) | 0.37 |
| Total bilirubin (µmol/L) | 12.0 (1.7-50.6) | 13.1 (0.0-65.3) | 0.74 |
| Creatinine (µmol/L) | 70.7 (17.7-113.2) | 75.6 (53.0-114.9) | 0.26 |
All continuous data are expressed as median (range).
*AST – aspartate aminotransferase, ALT- alanine aminotransferase.