. Author manuscript; available in PMC: 2015 Jan 22.

Published in final edited form as: Proteomics. 2010 Jul;10(13):2444–2457. doi: 10.1002/pmic.200900271

Table 2. The top ten pathways mapped in the human platelet versus the corresponding ranking in the rat platelet proteome.

Rank denoted the mapped rank of the pathway in human or rat platelet; Count denoted the number of proteins matched to the particular pathway;

Pathways	human			rat

	Rank	Count	p value ^a)	Rank	Count	p value
Focal adhesion	1	53	2.3E-08	2	36	7.8E-05
Regulation of actin cytoskeleton	2	50	2.0E-07	1	42	1.6E-07
Leukocyte transendothelial migration	3	28	2.3E-04	3	26	2.8E-05
Insulin signaling pathway	4	25	2.0E-02	4	21	8.4E-03
Tight junction	5	23	1.5E-02	6	19	2.8E-02
GAP junction	6	22	1.7E-03	9	14	5.8E-02
Glycolysis/Gluconeogenesis	7	22	1.8E-06	5	19	1.4E-07
Proteasome	8	20	3.7E-10	17	10	1.4E-04
Apoptosis	9	17	4.7E-02	N/A^b)	N/A	N/A
Adherens junction	10	17	1.3E-02	8	15	4.9E-03

^a)

value reflects a modified Fisher exact P value, the smaller means the more enriched.

^b)

N/A indicates the corresponding pathway was not significantly mapped.