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The graph indicates the age of pediatric patients at the time of application to the UDP. The first peak represents the congenital onset disease (applicants’ age 4–6 years) and the second peak represents the onset of disease symptoms at early school age (applicants’ age 16–18 years). The time between the onset of symptoms and the time of application indicates the lengthy diagnostic odyssey experienced by most UDP patients. UDP, Undiagnosed Diseases Program.
