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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Proteomics Clin Appl. 2014 Sep 15;8(0):783–795. doi: 10.1002/prca.201300077

Figure 6. Detection of Peptides from the Disease-Specific Igκ Light Chain.

Figure 6

Three peptides derived from RNA-seq and κ light chain assembly using tumor cells from Patient 1 were observed with LC-MRM in a serum sample with 0.2g/dl M-protein: VTITCR (A), SLIYAASSLQSGVPSK (B), and ANQDITNSLVWFQQK (C). Data are provided from Patient 2 to illustrate the uniqueness of the three peptides (B, D, and F, respectively).