Table 2.
Average sequencing read coverage for all drug resistance mutations identified in the ALIVE cohort
| Gene product | Drug resistance mutation* | Ave. sequencing read coverage |
|---|---|---|
| PR | L10IFVC | 297 |
| V11I | 294 | |
| G16E | 1022 | |
| K20RMITV | 1917 | |
| L24I | 1039 | |
| D30N | 2169 | |
| L33FIV | 3140 | |
| M36LIV | 3639 | |
| M46I/L | 2609 | |
| I50L/V | 3895 | |
| F53LY | 1213 | |
| I54VTALM | 2122 | |
| D60E | 3065 | |
| I62V | 3198 | |
| L63P | 3346 | |
| I64LMV | 2635 | |
| A71VITL | 3800 | |
| G73CSTA | 3045 | |
| V82ATFSL | 3300 | |
| L89VIM | 4199 | |
| L90M | 4982 | |
| I93LM | 5850 | |
| RT | M41L | 5014 |
| A62V | 4941 | |
| K70R | 4324 | |
| V75I | 10460 | |
| V77I | 4787 | |
| V90I | 4177 | |
| K103N | 6048 | |
| V106A/M/I | 6492 | |
| V108I | 7424 | |
| E138KAGQR | 7401 | |
| M184V/I | 5906 | |
| Y188LHC | 5283 | |
| G190ASE | 4708 | |
| P225H | 5764 | |
| M230LI | 8668 | |
| IN | S147G | 3123 |
*Boldface mutations are major drug resistance mutations, non-boldface mutations are accessory mutations.