Table 3.
Drug resistance mutations emerging after incarceration in the ALIVE cohort
Drug class | Mutation | Sample #(s) (% frequency) |
---|---|---|
Protease inhibitors | L10IFVC | 19 (7.9%) |
V11I | 25 (6.0%) | |
G16E | 25 (3.2%) | |
K20RMITV | 24 (7.0%) | |
M36LIV | 24 (5.5%) | |
M46IL | 27 (7.3%) | |
F53LY | 16 (5.1%) | |
I62V | 4 (15.3%) | |
I64LMV | 4 (13.7%) | |
G73CSTA | 6 (8.1%) | |
V77I | 13 (4.6%) | |
L89VIM | 22 (3.6%) | |
L90M | 6 (16.2%) | |
NRTI inhibitors | M41L | 2 (13.3%) |
A62V | 2 (3.1%) | |
M184V | 2 (99.9%), 5 (82.8%), 9 (99.8%), 10 (100%), 16 (56.6%), 23 (68.5%) | |
NNRTI inhibitors | K103N | 5 (100%), 10 (100%), 23 (99.8%) |
V108I | 23 (59.8%) | |
E138KAGQR | 16 (7.6%) | |
P225H | 23 (55.3%), 10 (99.9%) | |
Integrase inhibitors | S147G | 16 (7.6%) |
Boldface font = major mutation. Regular font = accessory mutation.