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. 2014 Dec 5;7:89. doi: 10.1186/s13041-014-0089-3

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© Talsma et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Genetic interactions between FKBP59 and ATPalpha . FKBP59; ATPalpha double mutants and ATPalpha*, FKBP59 RNAi flies were assayed and compared to ATPalpha* heterozygous controls. The RNAi knockdown was driven with da-Gal4. The genotypes in each graph are: ATPalpha*/+ (green), FKBP59 ^E03444 /+; ATPalpha*/+ (red), daGal4,ATPalpha*/+ (blue), and FKBP59-RNAi/+;daGal4,ATPalpha*/+ (orange). FKBP59 mutants significantly enhanced the ATPalpha ^DTS1 phenotype. The ATPalpha ^CJ5 phenotype is suppressed by both the FKBP59 mutant and RNAi. *p < 0.05, **p < 0.01, ***p < 0.001.