Figure 1.
Dynamic expression of FGF8, FGFRs and Sonic Hedgehog signaling pathway molecule mRNA during neural stem/progenitor cells differentiation in vitro was measured on day, 10 and 20 by reverse transcription-PCR.
aP < 0.05, vs. expression of the previous differentiation stage. The results were expressed as absorbance ratio of mRNA expression on day 10 or 20 to that of the neural stem/progenitor cell stage, which was assigned a value of 1 (mean ± SD, n = 4).
FGF: Fibroblast growth factor; FGFR: fibroblast growth factor receptor; NSCs/NPCs: neural stem/progenitor cells.