Table 1.
Parameter | McAdam et al. [ 1 ] | Michet et al. [ 2 ] | Trentham & Le [ 3 ] | Kong et al. [ 4 ] | Ananthakrishna et al. [ 6 ] | Mathew et al. [ 7 ] | Present study |
---|---|---|---|---|---|---|---|
Year of Publication | 1976 | 1986 | 1998 | 2003 | 2009 | 2012 | 2014 |
No. of patients | 159 | 112 | 66 | 12 | 7 | 30 | 26 |
Mean age at diagnosis | 44 | 51 | 46 | 34 | 40 | 43 | 45 |
Female: Male | 76:83 | 55:57 | 49:17 | 3:1 | 2.5:1 | 23:20 | 1.6:1 |
Auricular Chondritis (%) | 89 | 85 | 95 | 83 | 57 | 88 | 96.1 |
Saddle Nose (%) | NR | 29 | 20 | 17 | NR | NR | 11.5 |
Arthritis (%) | 81 | 52 | 85 | 75 | 43 | 60 | 53.8 |
Hearing impairment (%) | 46 | 30 | 42 | 17 | NR | 37 | 46.1 |
Ocular involvement (%) | 65 | 51 | 57 | 67 | 43 | 57 | 42.3 |
Laryngeal/tracheal involvement (%) | 56 | 48 | 67 | 50 | 43 | 37 | 11.5 |
Cardiovascular involvement (%) | 9 | 6 | 8 | 8 | 14.3* | NR | 11.5 |
Skin involvement (%) | 17 | 28 | 38 | 0 | 14.3* | NR | 26.9 |
Tracheostomy (%) | 6 | NR | 5 | 42 | NR | NR | 1* |
Death (%) | 6 | NR | 3 | 0 | 0 | NR | 8 |
*Single patient. Percentage may not be significant.