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. 2014 Dec 20;9:198. doi: 10.1186/s13023-014-0198-1

Table 1.

Comparison of present study patient characteristics with previously published data

Parameter McAdam et al. [ 1 ] Michet et al. [ 2 ] Trentham & Le [ 3 ] Kong et al. [ 4 ] Ananthakrishna et al. [ 6 ] Mathew et al. [ 7 ] Present study
Year of Publication 1976 1986 1998 2003 2009 2012 2014
No. of patients 159 112 66 12 7 30 26
Mean age at diagnosis 44 51 46 34 40 43 45
Female: Male 76:83 55:57 49:17 3:1 2.5:1 23:20 1.6:1
Auricular Chondritis (%) 89 85 95 83 57 88 96.1
Saddle Nose (%) NR 29 20 17 NR NR 11.5
Arthritis (%) 81 52 85 75 43 60 53.8
Hearing impairment (%) 46 30 42 17 NR 37 46.1
Ocular involvement (%) 65 51 57 67 43 57 42.3
Laryngeal/tracheal involvement (%) 56 48 67 50 43 37 11.5
Cardiovascular involvement (%) 9 6 8 8 14.3* NR 11.5
Skin involvement (%) 17 28 38 0 14.3* NR 26.9
Tracheostomy (%) 6 NR 5 42 NR NR 1*
Death (%) 6 NR 3 0 0 NR 8

*Single patient. Percentage may not be significant.