Table 3.
Treatment Modalities of Infantile BP Patients
| Treatment | No of cases (% of total N = 81) | Comments |
|---|---|---|
| Topical corticosteroids alone | N = 8 (9.9%) | Good response |
| Topical corticosteroids + IVIG | N = 1 (1.2%) | Several relapses for one year |
| Topical corticosteroids + erythromycin | N = 1 (1.2%) | Good response |
| Systemic +/− topical corticosteroids (+/− antibiotics) | N = 41 (50.6%) | Good response |
| Systemic corticosteroids + dapsone/ sulphapyridin (+/− antibiotics) | N = 16 (19.8%) | Good response |
| Dapsone/ sulphapyridin alone | N = 2 (2.5%) | One relapse under treatment. Same treatment was attempted in one other patient without success, so steroids were added. |
| No treatment | N = 1 | |
| N/A | N = 1 | |
| Corticosteroids +/− dapsone plus other medications due to poor response | N = 11 (13.7%) | |
| • Azathioprine | N = 1 | No response |
| • Cyclosporine | N = 2 | Good response in N = 1 Partial response in N = 1 |
| • Mycophenolate mofetil | N = 7 | Moderate response in N = 7 |
| • Erythromycin and nicotinamide | N = 8 | Good response in N = 3 Partial / uncertain response in N = 5 |
| • IVIG | N = 8 | Good response in N = 2 Partial/ uncertain response in N = 6 |
| • Rituximab | N = 3 | Good response N = 2. Partial response N = 1. One sudden death in one of those two patients after three months (child had congenital immune deficiency). |
| • Omalizumab | N = 1 | Good response |
IVIG: Intravenous immunoglobulins.