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. 2003 Mar 1;13(3):341–346. doi: 10.1101/gr.554603

Figure 4.

Figure 4.

Deletion in woolly monkey genomic DNA affecting the β3GalT5 gene. (A) The length of the LR-PCR product containing the β3GalT5 gene is 14 kb in humans and 6 kb in woolly monkeys. (B) Human–woolly monkey comparative 21q array data reveal that the ∼8-kb rearrangement in the LR-PCR product in (A) results in the deletion of three alternatively spliced noncoding exons of the β3GalT5 gene. The effect of deleting these three alternatively spliced noncoding exons on the expression of the single coding exon of β3Gal-T5 is not known. Analysis of the woolly monkey β3Gal-T5 coding exon (by examining the 21q array data and dideoxysequencing of ∼50% of the 933 translated bp) did not reveal the presence of stop codons.