Table 3.
Hazard ratios (HR) for African-American versus White ovarian cancer-specific mortality.
| Variables | Model 1a |
Model 2b |
Model 3c |
|||
|---|---|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | |
| Race | ||||||
| White | 1.00 (reference) | 0.004 | 1.00 (reference) | 0.003 | 1.00 (reference) | 0.10 |
| African-American | 1.54 (1.21, 1.94) | 1.59 (1.23, 2.04) | 1.32 (0.95, 1.84) | |||
| Stage at diagnosis | ||||||
| Early (FIGO I/II) | 1.00 (reference) | 0.0012 | 1.00 (reference) | 0.0016 | ||
| Late (FIGO III/IV) | 1.72 (1.24, 2.39) | 1.70 (1.22, 2.36) | ||||
| Pathologic grade | ||||||
| Low-grade | 1.00 (reference) | 0.47 | 1.00 (reference) | 0.54 | ||
| High-grade | 1.09 (0.86, 1.39) | 1.08 (0.85, 1.37) | ||||
| Histologic sub-type | ||||||
| All others | 1.00 (reference) | 0.48 | 1.00 (reference) | 0.51 | ||
| Serous | 1.08 (0.87, 1.33) | 1.07 (0.87, 1.32) | ||||
| Surgical debulking (missing = 25) | ||||||
| Optimal debulking | 1.00 (reference) | <0.0001 | 1.00 (reference) | <0.0001 | ||
| Suboptimal debulking | 2.08 (1.52, 2.83) | 2.12 (1.55, 2.90) | ||||
| Disadvantage | ||||||
| 1st–3rd Quartiles combined | 1.00 (reference) | 0.09 | ||||
| 4th Quartile (highest) | 1.28 (0.96, 1.70) | |||||
aAdjusted for age at diagnosis.
bAdjusted for age, stage at diagnosis, pathologic grade, histologic sub-type, and surgical debulking.
cAdjusted for age, stage at diagnosis, pathologic grade, histologic sub-type, surgical debulking, and concentrated disadvantage.